Fenofibrate

Cat. No. 4113

Fenofibrate C20H21ClO4 [49562-28-9]

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Chemical Name: 2-[4-(4-Chlorobenzoyl)phenoxy]-2-methylpropanoic acid isopropyl ester

Biological Activity

PPARα agonist; hypolipidemic. Attenuates insulin resistance and increases high-density lipoprotein-cholesterol in db/db mice.

Technical Data

M.Wt:
360.83
Formula:
C20H21ClO4
Solubility:
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Purity:
>99 %
Storage:
Store at RT
CAS No:
49562-28-9

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Safety Data Sheet: View Safety Data Sheet

References

Mandard et al (2004) The direct peroxisome proliferator-activated receptor target fasting-induced adipose factor (FIAF/PGAR/ANGPTL4) is present in blood plasma as a truncated protein that is increased by fenofibrate treatment. J.Biol.Chem. 279 34411. PMID: 15190076.

Park et al (2006) PPARα agonist fenofibrate improves diabetic nephropathy in db/db mice. Kidney Int. 69 1511. PMID: 16672921.

Balakumar et al (2011) Pleiotropic actions of fenofibrate on the heart. Pharmacol.Res. 63 8. PMID: 21093591.

If you know of a relevant citation for this product please let us know.

View Related Products by Target

Keywords: Fenofibrate, supplier, peroxisome, proliferator-activated, receptors, pparalpha, PPARa, PPARα, agonists

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