Cat. No. 4113
Chemical Name: 2-[4-(4-Chlorobenzoyl)phenoxy]-2-methylpropanoic acid isopropyl ester
Biological ActivityPPARα agonist; hypolipidemic. Attenuates insulin resistance and increases high-density lipoprotein-cholesterol in db/db mice.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Certificate of Analysis / Safety Data Sheet
Mandard et al (2004) The direct peroxisome proliferator-activated receptor target fasting-induced adipose factor (FIAF/PGAR/ANGPTL4) is present in blood plasma as a truncated protein that is increased by fenofibrate treatment. J.Biol.Chem. 279 34411. PMID: 15190076.
Park et al (2006) PPARα agonist fenofibrate improves diabetic nephropathy in db/db mice. Kidney Int. 69 1511. PMID: 16672921.
Balakumar et al (2011) Pleiotropic actions of fenofibrate on the heart. Pharmacol.Res. 63 8. PMID: 21093591.
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Keywords: Fenofibrate, supplier, peroxisome, proliferator-activated, receptors, pparalpha, PPARa, PPARα, agonists
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