Cat. No. 4113
Chemical Name: 2-[4-(4-Chlorobenzoyl)phenoxy]-2-me
Biological ActivityPPARα agonist; hypolipidemic. Attenuates insulin resistance and increases high-density lipoprotein-cholesterol in db/db mice.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Safety Data Sheet
Mandard et al (2004) The direct peroxisome proliferator-activated receptor target fasting-induced adipose factor (FIAF/PGAR/ANGPTL4) is present in blood plasma as a truncated protein that is increased by fenofibrate treatment. J.Biol.Chem. 279 34411. PMID: 15190076.
Park et al (2006) PPARα agonist fenofibrate improves diabetic nephropathy in db/db mice. Kidney Int. 69 1511. PMID: 16672921.
Balakumar et al (2011) Pleiotropic actions of fenofibrate on the heart. Pharmacol.Res. 63 8. PMID: 21093591.
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Keywords: Fenofibrate, supplier, peroxisome, proliferator-activated, receptors, pparalpha, PPARa, PPARα, agonists