Cat. No. 4089
Chemical Name: 3'-[α-Amino-p-methoxyhydrocinnamamido
Biological ActivityProtein synthesis inhibitor; leads to the premature release of polypeptide chains as polypeptidyl purine derivatives. Analog of the 3' end of aminoacyl-tRNA. Aminonucleoside antibiotic. Inhibits translation in both in vitro and in vivo systems. Also inhibits the transport of proteins into the mitochondria in vitro.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Safety Data Sheet
Azzam and Algranati (1973) Mechanism of puromycin action: fate of ribosomes after release of nascent polypeptide chains from polysomes. Proc.Nat.Acad.Sci. 70 3866.
Price and Verner (1993) Puromycin inhibits protein import into mitochondria by interfering with an intramitochondrial ATP-dependent reaction. Biochim.Biophys.Acta. 1150 89. PMID: 8334141.
If you know of a relevant citation for this product please let us know.
View Related Products by Target
Keywords: Puromycin dihydrochloride, supplier, Puromycin, antibiotics, protein, synthesis, inhibitors, inhibits, translation
Find multiple products by catalog number
New Products in this Area
Potent and selective TGR5 agonistNSC 617145
Werner syndrome helicase (WRN) helicase inhibitorT2AA
PCNA inhibitorSEN 1269
Amyloid-β aggregation inhibitor
Follow @Tocris on Twitter
Tocris is now actively tweeting. For regular updates on news, events and special offers, follow @Tocris on Twitter.