Cat. No. 4064
Chemical Name: 2-Fluoro-4-[1-(5-,6,7,8-tetrahydro-
Biological ActivityRXR agonist (Ki = 12 nM; EC50 = 43 nM at RXRα receptors). Displays similar RAR agonist activity to bexarotene; exhibits an apparent RXR binding affinity 75% greater than bexarotene.
Licensing InformationManufactured and sold under license from Arizona State University - Patent Pending
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Safety Data Sheet
Wagner et al (2009) Modeling, synthesis and biological evaluation of potential retinoid X receptor (RXR) selective agonists: novel analogues of 4-[1-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)ethynyl]benzoic acid (bexarotene). J.Med.Chem. 52 5950. PMID: 19791803.
If you know of a relevant citation for this product please let us know.
View Related Products by Target
Keywords: Fluorobexarotene, supplier, Fluorobexarotene, retinoid, x, rexinoids, rxr, agonists
Find multiple products by catalog number
New Products in this Area
High affinity aryl hydrogen receptor (AhR) agonistML 179
Selective liver receptor homolog 1 (LRH1) inverse agonistAC 186
Potent and selective ERβ agonist; neuroprotectiveIsotretinoin
Endogenous agonist for retinoic acid receptors; inducer of neuronal differentiationBTC
Selective estrogen receptor modulator (SERM)Rifaximin
Pregnane X receptor agonist; antibiotic
June 24 - 27, 2015
Booth Number: B11:25