Cat. No. 4064
Chemical Name: 2-Fluoro-4-[1-(5-,6,7,8-tetrahydro-
Biological ActivityRXR agonist (Ki = 12 nM; EC50 = 43 nM at RXRα receptors). Displays similar RAR agonist activity to bexarotene; exhibits an apparent RXR binding affinity 75% greater than bexarotene.
Licensing InformationManufactured and sold under license from Arizona State University - Patent Pending
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Certificate of Analysis / Safety Data Sheet
Wagner et al (2009) Modeling, synthesis and biological evaluation of potential retinoid X receptor (RXR) selective agonists: novel analogues of 4-[1-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)ethynyl]benzoic acid (bexarotene). J.Med.Chem. 52 5950. PMID: 19791803.
If you know of a relevant citation for this product please let us know.
View Related Products by Target
Keywords: Fluorobexarotene, supplier, Fluorobexarotene, retinoid, x, rexinoids, rxr, agonists