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PSB 0739

Cat. No. 3983

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Chemical Name: 1-Amino-9,10-dihydro-9,10-dioxo-4-[[4-(phenylamino)-3-sulfophenyl]amino]-2-anthracenesulfonic acid sodium salt

Biological Activity

Highly potent P2Y₁₂ receptor antagonist (K_i = 24.9 nM). Unlike clopidogrel (Cat. No. 2490), does not require bioactivation.

Licensing Information

Sold with the permission of the University of Bonn.

Technical Data

M.Wt:

609.54

Formula:

C₂₆H₁₇N₃Na₂O₈S₂

Solubility:

Soluble to 25 mM in water and to 10 mM in DMSO

Purity:

>96 %

Storage:

Desiccate at RT

CAS No:

1052087-90-7

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.

Resources

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch

Safety Data Sheet: View Safety Data Sheet

References

Baqi et al (2009) High-affinity, non-nucleotide-derived competitive antagonists of platelet P2Y₁₂ receptors. J.Med.Chem. 52 3784. PMID: 19463000.

Hoffmann et al (2009) Interaction of new, very potent non-nucleotide antagonists with Arg256 of the human platelet P2Y₁₂ receptor. J.Pharmacol.Exp.Ther. 331 648. PMID: 19690189.

Felix et al (2011) Development of a comprehensive set of P2 receptor pharmacological research compounds. Purinerg.Sig. 8 101. PMID: 22052555.

If you know of a relevant citation for this product please let us know.

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