Cat. No. 3947
Chemical Name: 4-[(3aR,4R,7S,7aS-rel)-1,3,3a,4,7,7
Biological ActivityNegative control for endo-IWR 1 (Cat.No. 3532). 25-fold less active than endo-IWR 1; exhibits decreased activity against the Wnt/β-catenin pathway.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Safety Data Sheet
Chen et al (2008) Small molecule-mediated disruption of Wnt-dependent signaling in tissue regeneration and cancer. Nature Chem.Biol. 5 100.
Lu et al (2009) Structure-activity relationship studies of small-molecule inhibitors of Wnt response. Bioorg.Med.Chem.Lett. 19 3825. PMID: 19410457.
If you know of a relevant citation for this product please let us know.
View Related Products by Product Action
Keywords: exo-IWR 1, supplier, endo-IWR, 1, endo-IWR1, negative, controls, Wnt, beta-catenin, b-catenin, β-catenin, Tocris Bioscience, β-catenin
Find multiple products by catalog number
New Products in this Area
Wnt pathway inhibitor
March 14 - 16, 2016
New Orleans, LA, USA