exo-IWR 1

Cat. No. 3947

exo-IWR 1 C25H19N3O3 [1127442-87-8]

Price and Availability

For exo-IWR 1 pricing & availability please select your country from the drop down menu:
By clicking submit you agree to accept a cookie from Tocris Bioscience. For details, please read our privacy and cookie policy.

Chemical Name: 4-[(3aR,4R,7S,7aS-rel)-1,3,3a,4,7,7a-Hexahydro-1,3-dioxo-4,7-methano-2H-isoindol-2-yl]-N-8-quinolinylbenzamide

Biological Activity

Negative control for endo-IWR 1 (Cat.No. 3532). 25-fold less active than endo-IWR 1; exhibits decreased activity against the Wnt/β-catenin pathway.

Technical Data

Soluble to 100 mM in DMSO
>99 %
Store at RT

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Safety Data Sheet: View Safety Data Sheet


Chen et al (2008) Small molecule-mediated disruption of Wnt-dependent signaling in tissue regeneration and cancer. Nature Chem.Biol. 5 100.

Lu et al (2009) Structure-activity relationship studies of small-molecule inhibitors of Wnt response. Bioorg.Med.Chem.Lett. 19 3825. PMID: 19410457.

If you know of a relevant citation for this product please let us know.

View Related Products by Target

Keywords: exo-IWR 1, supplier, endo-IWR, 1, endo-IWR1, negative, controls, Wnt, beta-catenin, b-catenin, β-catenin

Quick Order

Find multiple products by catalog number

divider line

Cancer Research Product Guide

Cancer Research Guide

Highlights over 350 products for cancer research. view PDF today.

divider line

New Product Guide


Highlights 130 new products added in the first half of 2015. View PDF today.

divider line

New Products in this Area

Foxy 5

Wnt5a peptide mimetic

Sign-up for new product e-alerts
divider line

Bio-Techne Events

Pharmacology 2015

Pharmacology 2015

December 15 - 17, 2015

London UK