Orphanin FQ (1-11)Cat No.
3932
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Price and Availability |
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Alternative Name: Nociceptin (1-11) |
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Biological Activity
Peptide fragment containing amino acids 1-11 of Nociceptin (Cat. No. 0910). Potent agonist of the ORL1/KOR-3 receptor (Ki = 55 nM); displays no affinity for opioid receptors, including μ, δ, κ1 and κ3 receptors (Ki >1000 nM). Displays analgesic properties in CD-1 mice.Certificate of Analysis / MSDS
References
Rossi et al (1997) Pharmacological characterization of orphanin FQ/nociceptin and its fragments. J.Pharmacol.Exp.Ther. 282 858. Rossi et al (1998) Orphanin FQ/nociceptin analgesia in the rat. Brain Res. 792 327. Reinscheid et al (1996) Structure-activity relationship studies on the novel neuropeptide orphanin FQ. J.Biol.Chem. 271 14163.If you know of a useful citation for this product please let us know.
Keywords: Orphanin FQ (1-11), Nociceptin, Receptors, agonists, NOP, ORL1, KOR-3, analgesic, opioid
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