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Ticlopidine hydrochloride

Cat No. 3931

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Chemical Name: 5-[(2-Chlorophenyl)methyl]-4,5,6,7-tetrahydrothieno[3,2 -c]pyridine hydrochloride

Biological Activity

Selective P2Y₁₂ receptor antagonist. Inhibits ADP-induced platelet aggregation and displays antithrombotic activity following oral administration in vivo.

Technical Data

M.Wt:

300.25

Formula:

C₁₄H₁₄ClNS.HCl

Solubility:

Soluble to 100 mM in water and to 100 mM in DMSO

Purity:

>99 %

Storage:

Desiccate at RT

CAS No:

[53885-35-1]

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis and MSDS.

Resources

Certificate of Analysis / MSDS

Certificate of Analysis: View current batch

Material Safety Data Sheet: View current batch

References

Michelson (2008) P2Y12 antagonism: promises and challenges. Arterioscler.Thromb.Vasc.Biol. 28 33. Savi and Herbert (2005) Clopidogrel and ticlopidine: P2Y12 adenosine diphosphate-receptor antagonists for the prevention of atherothrombosis. Semin.Thromb.Haemostas. 31 174. Sharis et al (1998) The antiplatelet effects of ticlopidine and clopidogrel. Ann.Int.Med. 129 394.

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Purinergic (P2Y) Receptors

Keywords: Ticlopidine hydrochloride, selective, P2Y12, purinergic, receptors, purinoceptors, antagonists

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