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SJ 172550Cat No.
3929
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Price and Availability |
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Chemical Name: 2-[2-Chloro-4-[(1,5-dihydro-3-methyl-5-oxo-1-phenyl-4H- pyrazol-4-ylidene)methyl]-6-ethoxyphenoxy]acetic acid methyl ester |
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Biological Activity
MDMX inhibitor. Reversibly binds MDMX and inhibits the MDMX-p53 interaction in cultured cells; frees p53 to induce apoptosis.Technical Data
M.Wt:428.87
Formula:C22H21ClN2O5
Solubility:Soluble to 100 mM in DMSO
Purity: >99 %
Storage:Store at +4°C
CAS No:[431979-47-4]
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis and MSDS.
Resources
Certificate of Analysis / MSDS
Certificate of Analysis: View current batch
Material Safety Data Sheet: View current batch
References
Reed et al (2010) Identification and characterization of the first small molecule inhibitor of MDMX. J.Biol.Chem. 285 10786.If you know of a useful citation for this product please let us know.
Keywords: SJ 172550, disrupts, p53, MDMX, interaction, inhibitors, SJ172550
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