Cat. No. 3896
Alternative Name: N 0923
Chemical Name: (6S)-5,6,7,8-Tetrahydro-6-[propyl[2
Biological ActivityDopamine D2 and D3 receptor agonist. Ki values are 13 and 0.71 nM for D2 and D3 respectively. Also has significant affinity for 5-HT1A and adrenergic α2B receptors. Exhibits antiparkinsonian acitivity.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Certificate of Analysis / Safety Data Sheet
Belluzzi et al (2004) N-0923, a selective dopamine D2 receptor agonist, is efficacious in rat and monkey models of Parkinson's disease. Mov.Disord. 9 147.
Scheller et al (2009) The in vitro receptor profile of rotigotine: a new agent for the treatment of Parkinson's disease. Naunyn.Schmiedebergs.Arch.Pharmacol. 379 73. PMID: 18704368.
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Keywords: Rotigotine hydrochloride, supplier, D2, D3, dopamine, agonists, receptor, N0923, parkinson's, parkinsons
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