TWS 119Cat No.
3835
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Price and Availability |
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Chemical Name: 3-[[6-(3-Aminophenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]o xyphenol ditrifluoroacetate |
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Biological Activity
Inhibitor of glycogen synthase kinase-3β (IC50 = 30 nM). Induces neuronal differentiation in pluripotent murine embryonal carcinoma cells and embryonic stem cells (ESCs).Technical Data
M.Wt:The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis and MSDS.
Resources
Certificate of Analysis / MSDS
References
Ding et al (2003) Synthetic small molecules that control stem cell fate. Proc.Natl.Acad.Sci. 100 7632. Kordes et al (2008) Canonical wnt signaling maintains the quiescent stage of hepatic stellate cells. Biochem.Biophys.Res.Comm. 367 116.If you know of a useful citation for this product please let us know.
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Keywords: TWS 119, TWS119, stem, cells, glycogen, synthase, kinases, gsk-3, gsk3, gsk-3b, gsk-3beta, gsk-3β, inhibitors, neuronal, differentiation
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