Ceftriaxone disodium salt
Cat. No. 3732
Chemical Name: 7-[[(2Z)-2-(2-Amino-4-thiazolyl)-2-
Biological Activityβ-lactam antibiotic. Displays neuroprotective activity in vivo via upregulation and increased activity of the EAAT2 glutamate transporter.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Certificate of Analysis / Safety Data Sheet
Rothstein et al (2005) β-Lactam antibiotics offer neuroprotection by increasing glutamate transporter expression. Nature 433 73. PMID: 15635412.
Lipski et al (2007) Neuroprotective potential of ceftriaxone in in vitro models of stroke. Neuroscience 146 617. PMID: 17363173.
Rawls et al (2007) The beta-lactam antibiotic, ceftriaxone, attenuates morphine-evoked hyperthermia in rats. Br.J.Pharmacol. 151 1095. PMID: 17592517.
If you know of a relevant citation for this product please let us know.
View Related Products by Target
Keywords: Ceftriaxone disodium salt, supplier, GLT-1, EAAT2, glutamate, transporters, activators, expression, Excitatory, Amino, Acid, Transporters, Monoamine, Neurotransmitter, antibiotics
Find multiple products by catalog number
New Products in this Area
Potent EAAT and VMAT inhibitor; cell permeableCongo Red
EAAT inhibitor; also an amyloid fibril-binding dyeLDN 212320
Increases EAAT2 expression; neuroprotectiveNomifensine
Potent noradrenalin and dopamine uptake inhibitor. Antidepressant
June 30 - July 2, 2014
Booth Number: 39