4,4-Pentamethylenepiperidine hydrochloride

Cat No. 3692

4,4-Pentamethylenepiperidine hydrochloride C10H19N.HCl [180-44-9]

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Chemical Name: 3-Azaspiro[5.5]undecane hydrochloride

Biological Activity

M2 proton channel blocker (IC50 = 0.92 μM). Inhibits influenza virus M2 protein (AM2).

Technical Data

M.Wt:
189.73
Formula:
C10H19N.HCl
Solubility:
Soluble to 100 mM in water and to 100 mM in DMSO
Storage:
Desiccate at RT
CAS No:
[180-44-9]

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis and MSDS.

Certificate of Analysis / MSDS

Certificate of Analysis: View current batch
Material Safety Data Sheet: View current batch

References

Wang et al (2009) Discovery of spiro-piperidine inhibitors and their modulation of the dynamics of the M2 proton channel from Influenza A Virus. J.Am.Chem.Soc. 131 8066.

If you know of a useful citation for this product please let us know.

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Keywords: 4,4-Pentamethylenepiperidine hydrochloride, M2, proton, channels, blockers, influenza, virus, M2, protein, AM2, modulators

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