Cat. No. 3625
Chemical Name: N-[(1,1-Dimethylethoxy)carbonyl]-L-
Biological ActivityPotent and reversible human cathepsin L inhibitor (IC50 = 56 nM). Displays no inhibitory activity at cathepsin G. Antimalarial; inhibits leishmaniasis.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Safety Data Sheet
Myers et al (2008) Identification and synthesis of a unique thiocarbazate cathepsin L inhibitor. Bioorg.Med.Chem.Lett. 18 210. PMID: 18060772.
Shah et al (2008) Kinetic characterization and molecular docking of a novel, potent and selective slow-binding inhibitor of human cathepsin L. Mol.Pharmacol. 74 34. PMID: 18403718.
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Keywords: SID 26681509, supplier, SID26681509, cathepsin, L, inhibitor, inhibits, cysteine, protease, antimalarial
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