Cat. No. 3625
Chemical Name: N-[(1,1-Dimethylethoxy)carbonyl]-L-
Biological ActivityPotent and reversible human cathepsin L inhibitor (IC50 = 56 nM). Displays no inhibitory activity at cathepsin G. Antimalarial; inhibits leishmaniasis.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Certificate of Analysis / Safety Data Sheet
Myers et al (2008) Identification and synthesis of a unique thiocarbazate cathepsin L inhibitor. Bioorg.Med.Chem.Lett. 18 210. PMID: 18060772.
Shah et al (2008) Kinetic characterization and molecular docking of a novel, potent and selective slow-binding inhibitor of human cathepsin L. Mol.Pharmacol. 74 34. PMID: 18403718.
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Keywords: SID 26681509, supplier, SID26681509, cathepsin, L, inhibitor, inhibits, cysteine, protease, antimalarial