PD 173212Cat No. 3552 |
Price and Availability |
|
Chemical Name: N-[[4-(1,1-Dimethylethyl)phenyl]methyl-N-methyl-L-leucy l-N-(1,1-dimethylethyl)-O-phenylmethyl)-L-tyrosinamide |
|
Biological Activity
Potent N-type voltage-gated calcium channel blocker (IC50 = 36 nM). Displays selectivity over K+, Na+ and L-type Ca2+ channels. Prevents tonic seizures in the audiogenic seizure model in vivo.Technical Data
M.Wt:The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis and MSDS.
Resources
Certificate of Analysis / MSDS
References
Hu et al (1999) Structure-activity relationships of N-methyl-N-aralkyl-peptidylamines as novel N-type calcium channel blockers. Bioorg.Med.Chem.Letts. 9 2151.If you know of a useful citation for this product please let us know.
Keywords: PD 173212, Potent, N-type, Ca2+, channel, blockers, Calcium, CaV, Channels, voltage-gated, voltage-dependent, PD173212
Buy Now / Print Quote
Find multiple products by catalog number
Print Quote Facility
Order via your purchasing department
It's now even easier to place orders via your purchasing department.
Simply add a product to your cart & click on the "Print Quote" button.
Calcium Imbalance and Neuroprotective Targets
Written by E. Besancon et al
'Calcium Imbalance and Neuro-protective Targets in Cerebral Ischemia & Brain Injury' highlights the key targets involved in stroke, trauma and neurodegeneration.
Signal Transduction Guide
A collection of more than 600 products for signal transduction research. View PDF today.
Antidepressants - Current and Future Targets
Written by P. Skolnich et al
'Antidepressants - Current and Future Targets' provides an overview of the current and future targets for the treatment of major depressive disorder.
New Products in this Area
Calcium channel blocker
RSS News Feed
Find out about new products as soon as they go live!
Click on the orange RSS button to read more about our RSS feed and actively opt in.