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NPE-caged-proton

Cat. No. 3512

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Alternative Name: NPE-caged-sulfate

Chemical Name: 1-(2-Nitrophenyl)ethyl sulfate sodium salt

Biological Activity

1-(2-nitrophenyl)ethyl caged proton that releases a proton and a sulfate ion upon photolysis. Generates rapid acidifications down to pH 2 (pH jumps).

Technical Data

M.Wt:

269.21

Formula:

C₈H₈NNaO₆S

Solubility:

Soluble to 100 mM in water and to 100 mM in DMSO

Purity:

>98 %

Storage:

Store at -20°C

CAS No:

1186195-63-0

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.

Resources

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch

Safety Data Sheet: View Safety Data Sheet

References

Barth and Corrie (2002) Characterization of a new caged proton capable of inducing large pH jumps. Biophys.J. 83 2864. PMID: 12414718.

Abbruzzetti et al (2005) Kinetics of proton release after flash photolysis of 1-(2-Nitrophenyl)ethyl sulfate (caged sulfate) in aqueous solution. J.Am.Chem.Soc. 127 9865. PMID: 15998092.

Peralvarez-Marin et al (2008) Time-resolved infrared spectroscopy of pH-induced aggregation of the Alzheimer Aβ_1-28 peptide. J.Mol.Biol. 379 589. PMID: 18462754.

If you know of a relevant citation for this product please let us know.

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