FERb 033

Cat. No. 3523

FERb 033 C13H9ClFNO3 [1111084-78-6]

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Chemical Name: 2-Chloro-3'-fluoro-3,4'-dihydroxy-[1,1-biphenyl]-4-carboxaldehyde oxime

Biological Activity

Potent and selective ERβ receptor agonist (Ki = 7.1 nM, EC50 = 4.8 nM). Displays 62-fold selectivity over ERα.

Technical Data

M.Wt:
281.67
Formula:
C13H9ClFNO3
Solubility:
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Purity:
>98 %
Storage:
Store at +4°C
CAS No:
1111084-78-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Safety Data Sheet: View Safety Data Sheet

References

Minutolo et al (2009) Structural evolutions of salicylaldoximes as selective agonists for estrogen receptor β. J.Med.Chem. 52 858. PMID: 19128016.

If you know of a relevant citation for this product please let us know.

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Keywords: FERb 033, supplier, FERb033, estrogen, ERbeta, ERb, ERβ, receptors, agonists, oestrogen, Tocris Bioscience, Estrogen and Related Receptor Agonists

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