R&D Systems Inc. Tocris Bioscience Boston Biochem

FERb 033

Cat. No. 3523

FERb 033 C13H9ClFNO3 [1111084-78-6]

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Chemical Name: 2-Chloro-3'-fluoro-3,4'-dihydroxy-[1,1-biphenyl]-4-carboxaldehyde oxime

Biological Activity

Potent and selective ERβ receptor agonist (Ki = 7.1 nM, EC50 = 4.8 nM). Displays 62-fold selectivity over ERα.

Technical Data

M.Wt:
281.67
Formula:
C13H9ClFNO3
Solubility:
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Purity:
>98 %
Storage:
Store at +4°C
CAS No:
1111084-78-6

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Safety Data Sheet: View Safety Data Sheet

References

Minutolo et al (2009) Structural evolutions of salicylaldoximes as selective agonists for estrogen receptor β. J.Med.Chem. 52 858. PMID: 19128016.

If you know of a relevant citation for this product please let us know.

View Related Products by Target

Keywords: FERb 033, supplier, FERb033, estrogen, ERbeta, ERb, ERβ, receptors, agonists, oestrogen

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