R&D Systems Inc. Tocris Bioscience Boston Biochem

(±)-CP 47497

Cat. No. 3500

(±)-CP 47497 C21H34O2 [70434-82-1]

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Chemical Name: rel-5-(1,1-Dimethylheptyl)-2-[(1R,3­S)-3-hydroxycyclohexyl]phenol

Biological Activity

Potent CB1 receptor agonist (Ki = 2.2 nM). Display 3 - 28-fold > potency than Δ9-THC (Cat. No. 2741). Exhibits analgesic, motor depressant, anticonvulsant and hypothermic effects in vivo.

Technical Data

M.Wt:
318.49
Formula:
C12H34O2
Solubility:
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Purity:
>98 %
Storage:
Store at -20°C
CAS No:
70434-82-1

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.

Resources

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
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Safety Data Sheet: View Safety Data Sheet

References

Weissman et al (1982) Cannabimimetic activity from CP-47,497, a derivative of 3-phenylcyclohexanol. J.Pharmacol.Exp.Ther. 223 516. PMID: 6290642.

Melvin et al (1993) Structure-activity relationships for cannabinoid receptor-binding and analgesic activity: studies of bicyclic cannabinoid analogs. Mol.Pharmacol. 44 1008. PMID: 8246904.

Huffman et al (2008) Synthesis and pharmacology of 1-deoxy analogs of CP-47,497 and CP-55,940. Bioorg.Med.Chem. 16 322. PMID: 17919913.

If you know of a relevant citation for this product please let us know.

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