R&D Systems Inc. Tocris Bioscience Boston Biochem

Histamine dihydrochloride

Cat. No. 3545

Histamine dihydrochloride C5H9N3.2HCl [56-92-8]

Price and Availability

For Histamine dihydrochloride pricing & availability please select your country from the drop down menu:
Submit
By clicking submit you agree to accept a cookie from Tocris Bioscience. For details, please read our privacy and cookie policy.

Chemical Name: 2-(4-Imidazolyl)ethylamine dihydrochloride

Biological Activity

Endogenous agonist at histamine receptors (H1-4). Released from mast cells and basophils and exhibits inflammatory, vasodilatory and bronchoconstrictory activity. Stimulates gastric acid secretion and acts as a neurotransmitter in vivo.

Technical Data

M.Wt:
184.07
Formula:
C5H9N3.2HCl
Solubility:
Soluble to 100 mM in water and to 100 mM in DMSO
Storage:
Desiccate at RT
CAS No:
56-92-8

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Safety Data Sheet: View Safety Data Sheet

References

Hill et al (1997) International union of pharmacology. XIII. Classification of histamine receptors. Pharmacol.Rev. 49 253. PMID: 9311023.

Maintz and Novak (2007) Histamine and histamine intolerance. Am.J.Clin.Nutr. 85 1185. PMID: 17490952.

Thurmond et al (2008) The role of histamine H1 and H4 receptors in allergic inflammation: the search for new antihistamines. Nat.Rev.Drug Discov. 7 41. PMID: 18172439.

If you know of a relevant citation for this product please let us know.

Keywords: Histamine dihydrochloride, supplier, Endogenous, histamine, receptor, agonists, H4, Receptors, Histamine, H1, H2, H3, histaminergic

Quick Order

Find multiple products by catalog number

divider line

Histamine Review

Histamine Review

Written by Iwan de Esch and Rob Leurs, leading experts. Request a copy or view PDF today.

divider line

New Therapies and Challenges in Asthma

Written by Peter J. Barnes

Asthma Poster

'New Therapies, Challenges, and Breakthroughs in Asthma' highlights key pathways and new therapies used to treat asthma, including those currently in clinical development.

divider line

New Product Guide

NPG

Highlights 140 new products added in the first half of 2014. Request a copy or view PDF today.

divider line

Bio-Techne Events

Pharmacology 2014

Pharmacology 2014

December 16 - 18, 2014

London, UK

Booth Number: 12