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PNU 177864 hydrochlorideCat No. 3355 |
Price and Availability |
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Chemical Name: N-[4-[2-(Propylamino)ethyl)phenyl]-4-(trifluoromethoxy) -benzenesulfonamide hydrochloride |
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Biological Activity
Highly selective dopamine D3 receptor antagonist. Induces phospholipidosis and exhibits antischizophrenic activity in vivo.Technical Data
M.Wt:438.89
Formula:C18H21F3N2O3S.HCl
Solubility:Soluble to 20 mM in water and to 100 mM in DMSO
Purity: >99 %
Storage:Desiccate at RT
CAS No:[250266-51-4]
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis and MSDS.
Resources
Certificate of Analysis / MSDS
Certificate of Analysis: View current batch
Material Safety Data Sheet: View current batch
References
Vonderfecht et al (2004) Myopathy related to administration of a cationic amphiphilic drug and the use of multidose drug distribution analysis to predict its occurrence. Toxicol.Pathol. 32 318. Rudmann et al (2004) Epididymal and systemic phospholipidosis in rats and dogs treated with dopamine D3 selective antagonist PNU-177864. Toxicol.Pathol. 32 326.If you know of a useful citation for this product please let us know.
Keywords: PNU 177864 hydrochloride, selective, D3, antagonists, Dopamine, Receptors, dopaminergic, PNU177864, hydrochloride
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