PNU 177864 hydrochloride

Cat No. 3355

PNU 177864 hydrochloride C18H21F3N2O3S.HCl [250266-51-4]

Price and Availability

For PNU 177864 hydrochloride pricing & availability please select your country from the drop down menu:
Submit

Chemical Name: N-[4-[2-(Propylamino)ethyl)phenyl]-4-(trifluoromethoxy) -benzenesulfonamide hydrochloride

Biological Activity

Highly selective dopamine D3 receptor antagonist. Induces phospholipidosis and exhibits antischizophrenic activity in vivo.

Technical Data

M.Wt:
438.89
Formula:
C18H21F3N2O3S.HCl
Solubility:
Soluble to 20 mM in water and to 100 mM in DMSO
Purity:
>99 %
Storage:
Desiccate at RT
CAS No:
[250266-51-4]

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis and MSDS.

Certificate of Analysis / MSDS

Certificate of Analysis: View current batch
Material Safety Data Sheet: View current batch

References

Vonderfecht et al (2004) Myopathy related to administration of a cationic amphiphilic drug and the use of multidose drug distribution analysis to predict its occurrence. Toxicol.Pathol. 32 318. Rudmann et al (2004) Epididymal and systemic phospholipidosis in rats and dogs treated with dopamine D3 selective antagonist PNU-177864. Toxicol.Pathol. 32 326.

If you know of a useful citation for this product please let us know.

View Related Products by Target

Keywords: PNU 177864 hydrochloride, selective, D3, antagonists, Dopamine, Receptors, dopaminergic, PNU177864, hydrochloride

Buy Now / Print Quote

Find multiple products by catalog number


divider line

Print Quote Facility

Order via your purchasing department

Print Quote Facility

It's now even easier to place orders via your purchasing department.

Simply add a product to your cart & click on the "Print Quote" button.

more
divider line

Neurobiology of Parkinson's Disease

Written by A. Schapira

Parkinson's Poster

'Neurobiology and Therapeutics of Parkinson's Disease' highlights the neurobiology of Parkinson's disease and highlights current and novel therapeutic interventions.

request
divider line

Dopamine Review

Dopamine Review

Written by Phillip G. Strange, a leading expert. Request a copy or view PDF today.

request
divider line

GPCRs and Signalling Networks

Written by M.J. Marinissen

GPCR Poster

'G-Protein-coupled Receptors and Signalling Networks' summarizes the intricate network of intracellular signalling pathways involved in GPCR function.

request
divider line

7-TM Receptor Signalling

Written by T. Kenakin et al

7-TM Poster

'Seven Transmembrane Receptor Signalling' highlights the multiple behaviors of 7-TMs including G-protein-dependent and -independent signaling as well as the concept of collateral efficacy

request
divider line

New Products in this Area

GSK 789472 hydrochloride

D3 antagonist. Also D2 partial agonist

Rotigotine hydrochloride

Dopamine D2/D3 agonist

Sign-up for new product e-alerts
divider line

New Product Guide

New Product Guide Spring 2010

Highlights over 250 new products added in 2009/10. Request a copy or view PDF today.

request