R&D Systems Inc. Tocris Bioscience Boston Biochem

PF 750

Cat. No. 3307

PF 750 C22H23N3O [959151-50-9]

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Chemical Name: N-Phenyl-4-(3-quinolinylmethyl)-1-piperidinecarboxamide

Biological Activity

Irreversible fatty acid amide hydrolase (FAAH) inhibitor (IC50 = 16.2 nM) that displays no activity at a range of other serine hydrolases. Selectively inhibits FAAH within the central nervous system. Orally active.

Technical Data

M.Wt:
345.44
Formula:
C22H23N3O
Solubility:
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Purity:
>98 %
Storage:
Store at RT
CAS No:
959151-50-9

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Safety Data Sheet: View Safety Data Sheet

References

Ahn et al (2007) Novel mechanistic class of fatty acid amide hydrolase inhibitors with remarkable selectivity. Biochemistry 46 13019. PMID: 17949010.

Mileni et al (2008) Structure-guided inhibitor design for human FAAH by interspecies active site conversion. Proc.Natl.Acad.Sci.USA 105 12820.

If you know of a relevant citation for this product please let us know.

Keywords: PF 750, supplier, Selective, FAAH, inhibitors, Anandamide, Amidase, Fatty, Acid, Amide, Hydrolases, PF750

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