Cat. No. 3307
Chemical Name: N-Phenyl-4-(3-quinolinylmethyl)-1-p
Biological ActivityIrreversible fatty acid amide hydrolase (FAAH) inhibitor (IC50 = 16.2 nM) that displays no activity at a range of other serine hydrolases. Selectively inhibits FAAH within the central nervous system. Orally active.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Safety Data Sheet
Ahn et al (2007) Novel mechanistic class of fatty acid amide hydrolase inhibitors with remarkable selectivity. Biochemistry 46 13019. PMID: 17949010.
Mileni et al (2008) Structure-guided inhibitor design for human FAAH by interspecies active site conversion. Proc.Natl.Acad.Sci.USA 105 12820.
If you know of a relevant citation for this product please let us know.
View Related Products by Target
Keywords: PF 750, supplier, Selective, FAAH, inhibitors, Anandamide, Amidase, Fatty, Acid, Amide, Hydrolases, PF750
Find multiple products by catalog number
New Products in this Area
Ces3 and Ces1f inhibitor968
Allosteric inhibitor of glutaminaseARN 272
FAAH-like anandamide transporter (FLAT) inhibitorML 349
Selective and reversible lysophospholipase 2 (LYPLA2) inhibitorJJKK 048
Potent and selective monoacylglycerol lipase (MAGL) inhibitorML 348
Selective and reversible lysophospholipase 1 (LYPLA1) inhibitorTAK 21d
Potent FAAH inhibitor
July 7 - 11, 2015
Rio de Janeiro, Brazil