Cat. No. 3307
Chemical Name: N-Phenyl-4-(3-quinolinylmethyl)-1-p
Biological ActivityIrreversible fatty acid amide hydrolase (FAAH) inhibitor (IC50 = 16.2 nM) that displays no activity at a range of other serine hydrolases. Selectively inhibits FAAH within the central nervous system. Orally active.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Certificate of Analysis / Safety Data Sheet
Ahn et al (2007) Novel mechanistic class of fatty acid amide hydrolase inhibitors with remarkable selectivity. Biochemistry 46 13019. PMID: 17949010.
Mileni et al (2008) Structure-guided inhibitor design for human FAAH by interspecies active site conversion. Proc.Natl.Acad.Sci.USA 105 12820.
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Keywords: PF 750, supplier, Selective, FAAH, inhibitors, Anandamide, Amidase, Fatty, Acid, Amide, Hydrolases, PF750
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