Metoprolol tartrateCat No. 3256 |
Price and Availability |
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Chemical Name: 1-[4-(2-Methoxyethyl)phenoxy]-3-[(1-methylethyl)amino]- 2-propanol hemitartrate |
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Biological Activity
Selective β1-adrenoceptor antagonist (Ki values are 47, 2960 and 10100 nM for β1, β2 and β3 adrenoceptors respectively). Inhibits spontaneous endothelin-1 production in vitro and displays antihypertensive and antianginal activity in vivo.Technical Data
M.Wt:The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis and MSDS.
Resources
Certificate of Analysis / MSDS
References
Garlichs et al (1999) Beta-blockers reduce the release and synthesis of endothelin-1 in human endothelial cells. Eur.J.Clin.Invest. 29 12. Hoffmann et al (2004) Comparative pharmacology of human β-adrenergic receptor subtypes - characterization of stably transfected receptors in CHO cells. Naunyn-Schmied.Arch.Pharmacol. 369 151. Dasbiswas et al (2008) S-metoprolol: The 2008 Clinical Review. J.Indian.Med.Assoc. 106 259.If you know of a useful citation for this product please let us know.
Keywords: Metoprolol tartrate, Selective, α1-adrenoceptor, beta1-adrenoceptor, b1-adrenoceptor, antagonists, b1-adrenergic, β1-Adrenergic, beta1-Adrenergic, Receptors
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