VU 0155041Cat No. 3248 |
Price and Availability |
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Chemical Name: cis-2-[[(3,5-Dichlorophenyl)amino]carbonyl]cyclohexanec arboxylic acid |
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Biological Activity
Potent, positive allosteric modulator/allosteric agonist at mGlu4 receptors (EC50 = 798 and 693 nM at human and rat mGlu4 receptors respectively). Active in in vivo models of Parkinson's disease following i.c.v. administration.Technical Data
M.Wt:The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis and MSDS.
Resources
Certificate of Analysis / MSDS
References
Niswender et al (2008) Discovery, characterization, and antiparkinsonian effect of novel positive allosteric modulators of metabotropic glutamate receptor 4. Mol.Pharmacol. 74 1345.If you know of a useful citation for this product please let us know.
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Keywords: VU 0155041, Potent, positive, allosteric, mGlu4, mGluR4, agonists, mGlur, Group, III, Receptors, Glutamate, Metabotropic, VU0155041
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