Cat. No. 3229
Biological ActivitySelective bradykinin B2 receptor agonist that is resistant to carboxypeptidase cleavage. 5-fold more potent and exhibits a more prolonged duration of action than bradykinin (Cat No. 3004) in vivo.
(Modifications: Phe-8 - Arg-9 peptide bond replaced with Ψ-(CH2-NH))
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Certificate of Analysis / Safety Data Sheet
Drapeau et al (1988) [Phe8Ψ(CH2-NH)Arg9]bradykinin, a B2 receptor selective agonist which is not broken down by either kininase I or kininase II. Eur.J.Pharmacol. 155 193. PMID: 2907489.
Marceau et al (2002) Kinin receptors: functional aspects. Int.Immunopharmacol. 2 1729. PMID: 12489786.
Leeb-Lundberg et al (2005) International union of pharmacology. XLV. Classification of the kinin receptor family: from molecular mechanisms to pathophysiological consequences. Pharmacol.Rev. 57 27. PMID: 15734727.
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Keywords: [Phe8Y(CH-NH)Arg9]-Bradykinin, supplier, Selective, B2, agonists, Bradykinin, Receptors, [Phe8psi(CH-NH)Arg9]-Bradykinin
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