Cat. No. 3208
Chemical Name: (1S,2R,8R,8aR)-Octahydro-1,2,8-indolizinetriol
Biological ActivityInhibitor of α-mannosidase II which inhibits glycoprotein processing. Displays anticancer and immune modulatory properties.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Certificate of Analysis / Safety Data Sheet
Tulsiani et al (1982) Swainsonine inhibits the biosynthesis of complex glycoproteins by inhibition of golgi mannosidase II. J.Biol.Chem. 257 7936. PMID: 6806288.
Olden et al (1991) The potential importance of swainsonine in therapy for cancers and immunology. Pharmacol.Ther. 50 285. PMID: 1754603.
Sun et al (2007) Inhibition of the growth of human gastric carcinoma in vivo and in vitro by swainsonine. Phytomedicine 14 353. PMID: 17097281.
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Keywords: Swainsonine, supplier, inhibitors, α-mannosidase, alpha-mannosidase, II, Glycosylases, Carbohydrate, Metabolism
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