R&D Systems Inc. Tocris Bioscience Boston Biochem

Camostat mesylate

Cat. No. 3193

Camostat mesylate C20H22N4O5.CH3SO3H [59721-29-8]

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Chemical Name: 4-[[4-[(Aminoiminomethyl)amino]benz­oyl]oxy]benzeneacetic acid 2-(dimethylamino)-2-oxoethyl ester methanesulfonate

Biological Activity

Orally active protease inhibitor. Known to inhibit trypsin and various inflammatory proteases including plasmin, kallikrein and thrombin. Suppresses pancreatitis-induced pain in rats following oral administration.

Technical Data

M.Wt:
494.52
Formula:
C20H22N4O5.CH3SO3H
Solubility:
Soluble to 100 mM in water and to 100 mM in DMSO
Purity:
>98 %
Storage:
Desiccate at RT
CAS No:
59721-29-8

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.

Certificate of Analysis / Safety Data Sheet

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Safety Data Sheet: View Safety Data Sheet

References

Horiuchi et al (1990) Gabexate and camostat, synthetic proteinase inhibitors, as direct inducing factors of water and bicarbonate secretion in the isolated and blood-perfused dog pancreas. J.Pharmacol.Exp.Ther. 252 320. PMID: 1688943.

Ishikura et al (2007) The proteinase inhibitor camostat mesilate suppresses pancreatic pain in rodents. Life Sci. 80 1999. PMID: 17433371.

If you know of a relevant citation for this product please let us know.

View Related Products by Target

Keywords: Camostat mesylate, supplier, Orally, active, protease, inhibitors, Proteases, Proteinases, trypsin, plasmin, kallikrein, thrombin

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