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Camostat mesylateCat No. 3193 |
Price and Availability |
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Chemical Name: 4-[[4-[(Aminoiminomethyl)amino]benzoyl]oxy]benzeneaceti c acid 2-(dimethylamino)-2-oxoethyl ester methanesulfonate |
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Biological Activity
Orally active protease inhibitor. Known to inhibit trypsin and various inflammatory proteases including plasmin, kallikrein and thrombin. Suppresses pancreatitis-induced pain in rats following oral administration.Technical Data
M.Wt:494.52
Formula:C20H22N4O5.CH3SO3H
Solubility:Soluble to 100 mM in water and to 100 mM in DMSO
Purity: >98 %
Storage:Desiccate at RT
CAS No:[59721-29-8]
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis and MSDS.
Resources
Certificate of Analysis / MSDS
Certificate of Analysis: View current batch
Material Safety Data Sheet: View current batch
References
Horiuchi et al (1990) Gabexate and camostat, synthetic proteinase inhibitors, as direct inducing factors of water and bicarbonate secretion in the isolated and blood-perfused dog pancreas. J.Pharmacol.Exp.Ther. 252 320. Ishikura et al (2007) The proteinase inhibitor camostat mesilate suppresses pancreatic pain in rodents. Life Sci. 80 1999.If you know of a useful citation for this product please let us know.
Keywords: Camostat mesylate, Orally, active, protease, inhibitors, Proteases, Proteinases, trypsin, plasmin, kallikrein, thrombin
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