Cat. No. 3124
Biological ActivitySelective antagonist of neuromuscular nicotinic receptors α1β1γδ. Displays selectivity for α/δ sites over α/γ sites in Torpedo.
Licensing InformationSold under license from University of Utah
(Modifications: X = Hyp, Cys-18 = C-terminal amide, Disulfide bridge between 4 - 10, 5 - 17)
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Certificate of Analysis / Safety Data Sheet
Martinez et al (1995) α-Conotoxin EI, a new nicotinic acetylcholine receptor antagonist with novel selectivity. Biochemistry 34 14519. PMID: 7578057.
Park et al (2001) Solution conformation of α-Conotoxin EI, a neuromuscular toxin specific for the α1/δ subunit interface of Torpedo nicotinic acetylcholine receptor. J.Biol.Chem. 276 49028. PMID: 11641403.
Lopez-Vera et al (2007) Novel α-conotoxins from Conus spurius and the α-conotoxin EI share high-affinity potentiation and low-affinity inhibition of nicotinic acetylcholine receptors. FEBS Lett. 274 3972.
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Keywords: a-Conotoxin EI, supplier, α1β1δγ, alpha1beta1deltagamma, a1b1dg, selective, nAChR, antagonists, Acetylcholine, Nicotinic, Receptors, Non-Selective, Subtypes, Other, α-conotoxin, alpha-conotoxin, EI, a-ConotoxinEI, conotoxin