Cat. No. 3123
Biological ActivitySelective antagonist of α3β2 nAChR receptors (IC50 values are 9.56 and 252 nM for α3β2 and α7 receptors respectively).
Licensing InformationSold under license from University of Utah
(Modifications: Cys-16 = C-terminal amide, Disulfide bridge between 2 - 8, 3 - 16)
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Certificate of Analysis / Safety Data Sheet
Fainzilber et al (1994) New mollusc-specific α-conotoxins block Aplysia neuronal acetylcholine receptors. Biochemistry 33 9523. PMID: 8068627.
Luo et al (1999) Single-residue alteration in α-conotoxin PnIA switches its nAChR subtype selectivity. Biochemistry 38 14542. PMID: 10545176.
Everhart et al (2003) Identification of residues that confer α-conotoxin-PnIA sensitivity on the α3 subunit of neuronal nicotinic acetylcholine receptors. J.Pharmacol.Exp.Ther. 306 664. PMID: 12734390.
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Keywords: a-Conotoxin PnIA, supplier, Selective, α3β2, alpha3beta2, a3b2, nAChR, antagonists, Acetylcholine, Nicotinic, Receptors, Non-Selective, Subtypes, Other, α-conotoxin, alpha-conotoxin, PnIA, conotoxin
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