Cat. No. 3120
Biological ActivitySelective antagonist of α3β4 nicotinic acetylcholine receptors. Displays > 100-fold selectivity over other receptor subunit combinations including α2β2, α2β4, α3β2, α4β2, α4β4 and α1β1γδ.
Licensing InformationSold under license from University of Utah
(Modifications: Cys-15 = C-terminal amide, Disulfide bridge between 2 - 8, 3 - 15)
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Certificate of Analysis / Safety Data Sheet
Luo et al (1998) α-Conotoxin AuIB selectively blocks α3β4 nicotinic acetylcholine receptors and nicotine-evoked norepinephrine release. J.Neurosci. 18 8571. PMID: 9786965.
Nai et al (2003) Relating neuronal nicotinic acetylcholine receptor subtypes defined by subunit composition and channel function. Mol.Pharmacol. 63 311. PMID: 12527802.
Park et al (2006) An α3β4 subunit combination acts as a major functional nicotinic acetylcholine receptor in male rat pelvic ganglion neurons. Pflugers Arch. 452 775. PMID: 16715294.
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Keywords: a-Conotoxin AuIB, supplier, Selective, α3β4, alpha3β4, beta4, a3b4, nAChR, antagonists, Acetylcholine, Nicotinic, Receptors, Non-Selective, Subtypes, Other, α-conotoxin, alpha-conotoxin, AulB, a-conotoxin, conotoxin