JNJ 1661010

Cat No. 3262

JNJ 1661010 C19H19N5OS [681136-29-8]

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Chemical Name: N-Phenyl-4-(3-phenyl-1,2,4-thiadiazol-5-yl)-1-piperazin ecarboxamide

Biological Activity

Selective, reversible inhibitor of fatty acid amide hydrolase (FAAH) (IC50 = 12nM). Brain penetrant and active in vivo.

Technical Data

M.Wt:
365.45
Formula:
C19H19N5OS
Solubility:
Soluble to 100 mM in DMSO and to 10 mM in ethanol
Purity:
>99 %
Storage:
Store at +4°C
CAS No:
[681136-29-8]

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis and MSDS.

Certificate of Analysis / MSDS

Certificate of Analysis: View current batch
Material Safety Data Sheet: View current batch

References

Keith et al (2008) Thiadiazolopiperazinyl ureas as inhibitors of fatty acid amid hydrolase. Bioorg.Med.Chem.Lett. 18 4838.

If you know of a useful citation for this product please let us know.

Keywords: JNJ 1661010, Selective, reversible, FAAH, inhibitors, Anandamide, Amidase, Fatty, Acid, Amide, Hydrolases, JNJ1661010

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