Cat. No. 3097
Biological ActivityBacterial toxin that catalyzes ADP-ribosylation of G-proteins Gi, Go and Gt. Impairs G protein heterotrimer interaction with receptors, blocking receptor coupling.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Safety Data Sheet
Bokoch et al (1983) Indentification of the predominant substrate for ADP-ribosylation by islet activating protein. J.Biol.Chem. 258 2072. PMID: 6296122.
Barbieri and Cortina (1988) ADP-ribosyltransferase mutations in the catalytic S-1 subunit of pertussis toxin. Infect.Immun. 56 1934. PMID: 3135265.
Casey et al (1989) G protein βγ subunits from bovine brain and retina: equivalent catalytic support of ADP-ribosylation of a subunits by pertussis toxin but differential interactions with Gsa. Biochemistry 28 611. PMID: 2496748.
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Keywords: Pertussis Toxin, supplier, Catalyzes, ADP-ribosylation, G-Protein, Heterotrimeric, Gi, Go, Gt, toxin
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