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Pertussis Toxin

Cat. No. 3097

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Biological Activity

Bacterial toxin that catalyzes ADP-ribosylation of G-proteins G_i, G_o and G_t. Impairs G protein heterotrimer interaction with receptors, blocking receptor coupling.

Technical Data

Storage:

Store at +4°C

CAS No:

70323-44-3

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.

Resources

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch

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Safety Data Sheet: View Safety Data Sheet

References

Bokoch et al (1983) Indentification of the predominant substrate for ADP-ribosylation by islet activating protein. J.Biol.Chem. 258 2072. PMID: 6296122.

Barbieri and Cortina (1988) ADP-ribosyltransferase mutations in the catalytic S-1 subunit of pertussis toxin. Infect.Immun. 56 1934. PMID: 3135265.

Casey et al (1989) G protein βγ subunits from bovine brain and retina: equivalent catalytic support of ADP-ribosylation of a subunits by pertussis toxin but differential interactions with G_sa. Biochemistry 28 611. PMID: 2496748.

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