Cat. No. 1362
Alternative Names: Iodoresiniferatoxin, 5'-IRTX
Chemical Name: 6,7-Deepoxy-6,7-didehydro-5-deoxy-2
Biological ActivityPotent and silent vanilloid receptor antagonist, 40-fold more potent than capsazepine (Cat. No. 0464). Binds to TRPV1 (VR1) receptors expressed in HEK293 cells with a Ki of 5.8 nM.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Safety Data Sheet
Seabrook et al (2001) Properties of iodo-resiniferatoxin - a high affinity VR1 vanilloid receptor antagonist. Soc.Neurosci.Abstr. 925.9.
Wahl et al (2001) Iodo-resiniferatoxin, a new potent vanilloid receptor antagonist. Mol.Pharmacol. 59 9. PMID: 11125018.
Marinelli et al (2002) Capsaicin activation of glutamatergic synaptic transmission in the rat locus coeruleus in vitro. J.Physiol. 543 531. PMID: 12205187.
If you know of a relevant citation for this product please let us know.
Keywords: 5'-Iodoresiniferatoxin, supplier, Potent, silent, TRPV1, antagonists, Vanillioid, Receptors, VR1, Channels, Transient, Receptor, Potential, 5-Iodoresiniferatoxin, 5-IRTX
Find multiple products by catalog number
New Products in this Area
Potent TRPM8 antagonistASP 7663
Selective TRPA1 activatorRQ 00203078
Potent and selective TRPM8 antagonist; orally activeM8 B hydrochloride
Potent and selective TRPM8 channel blockerClemizole hydrochloride
TRPC5 blocker; also H1 antagonist
July 7 - 11, 2015
Rio de Janeiro, Brazil