Cat. No. 0380
Chemical Name: N-(1-Azabicyclo[2.2.2]oct-3-yl)-6-c
Biological ActivityA selective and potent 5-HT3 antagonist (Ki = 2.9 nM).
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Safety Data Sheet
Fukuda et al (1991) The antiemetic profile of Y-25130, a new selective 5-HT3 receptor antagonist. Eur.J.Pharmacol. 196 299. PMID: 1654255.
Sato et al (1992) Antagonistic activity of Y-25130 on 5-HT3 receptors. Jpn.J.Pharmacol. 59 443. PMID: 1331590.
Haga et al (1993) The effects of orally administered Y-25130, a selective serotonin3 receptor antagonist on chemotherapeutic agent-induced emesis. Jpn.J.Pharmacol. 63 377. PMID: 8107329.
If you know of a relevant citation for this product please let us know.
View Related Products by Target
Keywords: Y-25130 hydrochloride, supplier, Potent, selective, 5-HT3, antagonists, Serotonin, Receptors
Find multiple products by catalog number
New Products in this Area
Potent and selective P2X7 antagonist; brain penetrant
Follow @Tocris on Twitter
Tocris is now actively tweeting. For regular updates on news, events and special offers, follow @Tocris on Twitter.