Dextromethorphan hydrobromide

Cat. No. 3071

Dextromethorphan hydrobromide C18H25NO.HBr [6700-34-1]

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Chemical Name: (9α,13α,14α)-3-Methoxy-17-methylmorphinan hydrobromide

Biological Activity

Non-competitive, low affinity NMDA receptor antagonist. Antitussive, anticonvulsive and neuroprotective agent.

Technical Data

Soluble to 40 mM in water
>99 %
Store at RT

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Safety Data Sheet: View Safety Data Sheet


Choi et al (1987) Dextrorophan and levorphanol selectively block N-methyl-D-aspartate receptor-mediated neurotoxicity on corticol neurons. J.Pharmacol.Exp.Ther. 242 713. PMID: 3039122.

Keller et al (2008) Dextromethorphan is protective against sensitized N-methyl-D-aspartate receptor-mediated excitotoxic brain damage in the developing mouse brain. Eur.J.Neurosci. 27 874. PMID: 18279363.

If you know of a relevant citation for this product please let us know.

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Keywords: Dextromethorphan hydrobromide, supplier, NMDA, receptor, antagonists, Glutamate, Receptors, N-Methyl-D-Aspartate, iGluR, Ionotropic, NMDA Receptor Antagonists

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