R&D Systems Inc. Tocris Bioscience Boston Biochem

Ellagic acid

Cat. No. 3058

Ellagic acid C14H6O8 [476-66-4]

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Chemical Name: 2,3,7,8-Tetrahydroxy-[1]benzopyrano[5,4,3-cde][1]benzopyran-5,10-dione

Biological Activity

Selective, ATP-competitive inhibitor of casein kinase 2 (CK2) (IC50 values are 40, 2900, 3500, 4300 and 9400 nM for CK2, Lyn, PKA, Syk  and FGR respectively). Exhibits antioxidant, antitumor and anticarcinogenic activity and also inhibits glutathione S-transferase.

Technical Data

M.Wt:
302.19
Formula:
C14H6O8
Solubility:
Soluble to 0.65 mM in ethanol
Purity:
>99 %
Storage:
Store at RT
CAS No:
476-66-4

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Safety Data Sheet: View Safety Data Sheet

References

Cozza et al (2006) Identification of ellagic acid as potent inhibitor of protein kinase CK2: a successful example of a virtual screening application. J.Med.Chem. 49 2363. PMID: 16610779.

Han et al (2006) Antioxidant and apoptosis-inducing activities of ellagic acid. Anticancer Res. 26 3601. PMID: 17094489.

Hayeshi et al (2007) The inhibition of human glutathione S-transferases activity by plant polyphenolic compounds ellagic acid and curcumin. Food Chem.Toxicol. 45 286. PMID: 17046132.

If you know of a relevant citation for this product please let us know.

View Related Products by Target

Keywords: Ellagic acid, supplier, Selective, CK2, inhibits, inhibitors, glutathione, S-transferase, Casein, Kinase, 2, Transferases

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