Cat. No. 3058
Chemical Name: 2,3,7,8-Tetrahydroxy-benzopyrano
Biological ActivitySelective, ATP-competitive inhibitor of casein kinase 2 (CK2) (IC50 values are 40, 2900, 3500, 4300 and 9400 nM for CK2, Lyn, PKA, Syk and FGR respectively). Exhibits antioxidant, antitumor and anticarcinogenic activity and also inhibits glutathione S-transferase.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Safety Data Sheet
Cozza et al (2006) Identification of ellagic acid as potent inhibitor of protein kinase CK2: a successful example of a virtual screening application. J.Med.Chem. 49 2363. PMID: 16610779.
Han et al (2006) Antioxidant and apoptosis-inducing activities of ellagic acid. Anticancer Res. 26 3601. PMID: 17094489.
Hayeshi et al (2007) The inhibition of human glutathione S-transferases activity by plant polyphenolic compounds ellagic acid and curcumin. Food Chem.Toxicol. 45 286. PMID: 17046132.
If you know of a relevant citation for this product please let us know.
View Related Products by Product Action
Keywords: Ellagic acid, supplier, Selective, CK2, inhibits, inhibitors, glutathione, S-transferase, Casein, Kinase, 2, Transferases, Casein Kinase 2 Inhibitors
Find multiple products by catalog number
New Products in this Area
PDGFRβ, B-Raf, c-Raf, FLT3 and KIT inhibitorNilvadipine
Syk kinase inhibitor; inhibits Aβ productionCentrinone B
High affinity and selective PLK4 inhibitorHTH 01-015
Potent and selective NUAK1 inhibitorKobe 0065
H-Ras-cRaf1 interaction inhibitor; inhibits Raf signalingOSU 03012
PDK1 inhibitor; inhibits Akt signalingSR 7826
Potent and selective LIMK inhibitor; antitumorMps BAY 2a
Potent and selective Mps1 kinase inhibitorNG 25
TGF-β-activated kinase (TAK1) inhibitorMI 14
Potent and selective PI 4-kinase IIIβ inhibitorCTA 056
ITK inhibitorAZD 1480
Potent and selective JAK2 inhibitor; antiangiogenicTC-S 7001
Potent and highly selective ROCK inhibitor; orally activeAS 2444697
Potent and selective IRAK4 inhibitorBS 181 dihydrochloride
Selective cdk7 inhibitorA66
Potent and selective PI 3-kinase p110α inhibitorAZ 191
Potent DYRK1B inhibitorETP 45658
Potent PI 3-kinase inhibitor; also inhibits DNA-PK and mTORPFK 15
PFKFB3 inhibitorPD 0332991 isethionate
Potent, selective Cdk4/6 inhibitor; brain penetrant
December 15 - 17, 2015