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Ellagic acidCat. No. 3058 |
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Chemical Name: 2,3,7,8-Tetrahydroxy-[1]benzopyrano[5,4,3-cde][1]benzopyran-5,10-dione |
Biological Activity
Selective, ATP-competitive inhibitor of casein kinase 2 (CK2) (IC50 values are 40, 2900, 3500, 4300 and 9400 nM for CK2, Lyn, PKA, Syk and FGR respectively). Exhibits antioxidant, antitumor and anticarcinogenic activity and also inhibits glutathione S-transferase.Certificate of Analysis / Safety Data Sheet
References
Cozza et al (2006) Identification of ellagic acid as potent inhibitor of protein kinase CK2: a successful example of a virtual screening application. J.Med.Chem. 49 2363. PMID: 16610779.
Han et al (2006) Antioxidant and apoptosis-inducing activities of ellagic acid. Anticancer Res. 26 3601. PMID: 17094489.
Hayeshi et al (2007) The inhibition of human glutathione S-transferases activity by plant polyphenolic compounds ellagic acid and curcumin. Food Chem.Toxicol. 45 286. PMID: 17046132.
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Keywords: Ellagic acid, supplier, Selective, CK2, inhibits, inhibitors, glutathione, S-transferase, Casein, Kinase, 2, Transferases
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