Cat. No. 3051
Biological ActivityVGF-derived peptide; spans residues 556-576 of the precursor sequence. Protects cerebellar granule cells (CGCs) from serum and potassium deprivation-induced apoptosis. Increases energy expenditure and prevents early phase diet-induced diabetes.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Safety Data Sheet
Bartolomucci et al (2006) TLQP-21, a VGF-derived peptide, increases energy expenditure and prevents the early phase of diet-induced obesity. Proc.Natl.Acad.Sci. USA 103 14584.
Jethwa et al (2007) VGF-derived peptide, TLQP-21, regulates food intake and body weight in Siberian hamsters. Endocrinol. 148 4044.
Severini et al (2008) TLQP-21, a neuroendocrine VGF-derived peptide, prevents cerebellar granule cell death induced by serum and potassium deprivation. J.Neurochem. 104 534. PMID: 18173805.
If you know of a relevant citation for this product please let us know.
View Related Products by Target
Keywords: TLQP 21, supplier, VGF-derived, peptide, Neurotrophin, Receptors, TLQP21
Find multiple products by catalog number
New Products in this Area
Potent EGFR and VEGFR inhibitorXL 184
Potent VEGFR inhibitor; also inhibits other RTKsPKI 166 hydrochloride
Potent EGFR-kinase inhibitorASP 3026
Potent anaplastic lymphoma kinase (ALK) inhibitorKYL
EphA4 receptor tyrosine kinase inhibitor; neuroprotectivePD 90780
Inhibits NGF binding to p75NTRLM11A 31 dihydrochloride
Nonpeptide p75NTR ligand; neuroprotectiveEG 00229
Neuropilin 1 (NRP1) receptor antagonist; inhibits VEGFA binding to NRP1
March 24 - 27, 2015