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Pemoline

Cat. No. 3045

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Alternative Names: Phenoxazole, Phenylisohydantoin

Chemical Name: 2-Amino-5-phenyl-4(5H)-oxazolone

Biological Activity

Long-acting central stimulant that induces self-injurious behavior in rats. Acts as an indirect monoamine agonist.

Technical Data

M.Wt:

176.17

Formula:

C₉H₈N₂O₂

Solubility:

Soluble to 10 mM in ethanol with gentle warming

Purity:

>99 %

Storage:

Store at RT

CAS No:

2152-34-3

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.

Resources

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch

Safety Data Sheet: View Safety Data Sheet

References

Mueller and Nyhan (1982) Pharmacologic control of pemoline induced self-injurious behavior in rats. Pharmacol.Biochem.Behav. 16 957. PMID: 6213967.

Kies and Devine (2004) Self-injurious behaviour: a comparison of caffeine and pemoline models in rats. Pharmacol.Biochem.Behav. 79 587. PMID: 15582667.

Muehlmann et al (2008) Pemoline (2-Amino-5-phenyl-1,3-oxazol-4-one)-induced self-injurious behavior: a rodent model of pharmacotherapeutic efficacy. J.Pharmacol.Exp.Ther. 324 214. PMID: 17925479.

If you know of a relevant citation for this product please let us know.

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