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D-erythro-Sphingosine (synthetic)Cat. No. 0633 |
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Chemical Name: trans-D-erythro-2-Amino-4-octadecene-1,3-diol |
Biological Activity
Inhibitor of protein kinase C and calmodulin-dependent enzymes, but may stimulate mast cells by activation of protein kinase C.Technical Data
M.Wt:The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Certificate of Analysis / Safety Data Sheet
References
Merrill et al (1989) Structural requirements for long-chain (sphingoid) base inhibition of protein kinase C in vitro and for the cellular effects of these compounds. Biochemistry 28 3138. PMID: 2742830.
Grossman (1990) Sphingosine inhibition and promotion of histamine release from isolated rat mast cells. Agents Actions 31 171. PMID: 1707581.
If you know of a relevant citation for this product please let us know.
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Keywords: D-erythro-Sphingosine (synthetic), supplier, Protein, kinase, C, inhibitors, PKC, Kinases
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