Cat. No. 0593
Chemical Name: 5-Nitro-2-(3-phenylpropylamino)benz
Biological ActivityInhibits calcium-sensitive chloride currents (10 μM). Putative GPR35 agonist.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Certificate of Analysis / Safety Data Sheet
Wangemann et al (1986) Cl--channel blockers in the thick ascending limb of the loop of Henle. Structure-activity relationship. Pflugers Arch. 407 S128. PMID: 2434915.
Keeling et al (1991) Effects of NPPB (5-nitro-1-(3-phenylpropylamino)benzoic acid on chloride transport in intestinal tissues and the T84 cell line. Biochim.Biophys.Acta 115 42. PMID: 1720331.
Kirkup et al (1996) Investigation of the effects of 5-nitro-2-(3-phenylpropylamino)-benzoic acid (NPPB) on membrane currents in rat portal vein. Br.J.Pharmacol. 117 175. PMID: 8825360.
Taniguchi et al (2008) 5-nitro-2-(3-phenylpropylamino)benzoic acid is a GPR35 agonist Pharmacology 82 245. PMID: 18818509.
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Keywords: NPPB, supplier, Chloride, channel, blockers, Cl-, Channels
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