R&D Systems Inc. Tocris Bioscience Boston Biochem

Mastoparan

Cat. No. 1192

Mastoparan Ile-Asn-Leu-Lys-Ala-Leu-Ala-Ala-Leu-Ala-Lys-Lys-Ile-Leu-NH2

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Biological Activity

Peptide activator of Gi and Go.

Technical Data

M.Wt:
1479
Formula:
C70H131N19O15
Sequence:
INLKALAALAKKIL

(Modifications: Leu-14 = C-terminal amide)

Solubility:
Soluble to 2.60 mg/ml in water
Storage:
Desiccate at -20°C
CAS No:
72093-21-1

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
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Safety Data Sheet: View Safety Data Sheet

References

Mousli et al (1990) G protein activation: a receptor-independent mode of action for cationic amphiphilic neuropeptides and venom peptides. TiPS 11 358. PMID: 2122563.

Higashijima and Ros (1991) Mapping of the mastoparan-binding site on G proteins. Cross-linking of [125I-Tyr3,Cys11]mastoparan to Go. J.Biol.Chem. 266 12655. PMID: 1905730.

Raynor et al (1991) Membrane interactions of amphiphilic polypeptides mastoparan, melittin, plymixin B and cardiotoxin. J.Biol.Chem. 266 2753. PMID: 1847132.

Longland et al (1999) The mechanism of inhibition of the Ca2+-ATPase by mastoparan. J.Biol.Chem. 274 14799. PMID: 10329678.

If you know of a relevant citation for this product please let us know.

View Related Products by Target

Keywords: Mastoparan, supplier, Activator, Gi, Go, Gi/o, G-Protein, Signaling, Signalling, Heterotrimeric

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