CGRP 8-37 (human)

Cat. No. 1181

CGRP 8-37 (human) Val-Thr-His-Arg-Leu-Ala-Gly-Leu-Leu-Ser-Arg-Ser-Gly-Gly-Val-Val-Lys-Asn-Asn-Phe-Val-Pro-Thr-Asn-Val-Gly-Ser-Lys-Ala-Phe-NH2

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Alternative Name: Calcitonin Gene-Related Peptide 8-37 (human)

Biological Activity

Peptide antagonist for CGRP1 receptors.

Technical Data

M.Wt:
3125.64
Formula:
C139H230N44O38
Sequence:
VTHRLAGLLSRSGGVVKNNFVPTNVGSKAF

(Modifications: Phe-30 = C-terminal amide)

Solubility:
Soluble to 0.50 mg/ml in water
Storage:
Desiccate at -20°C
CAS No:
119911-68-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
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Safety Data Sheet: View Safety Data Sheet

References

Poyner (1995) Pharmacology of receptors for calcitonin gene-related peptide and amylin. TiPS 16 424. PMID: 8578616.

Nakamura et al (1998) Calcitonin gene-related peptide as a GH secretagogue in human and rat pituitary somatotrophs. Brain Res. 807 203. PMID: 9757038.

Poyner et al (1998) Structural determinants for binding to CGRP receptors expressed by human SK-N-MC and Col 29 cells: studies with chimeric and other peptides. Br.J.Pharmacol. 124 1659. PMID: 9756381.

Wisskirchen et al (1998) Pharmacological characterization of CGRP receptors mediating relaxation of the rat pulmonary artery and inhibition of twitch responses of the rat vas deferens. Br.J.Pharmacol. 123 1673. PMID: 9605575.

If you know of a relevant citation for this product please let us know.

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Keywords: CGRP 8-37 (human), supplier, CGRP1, receptor, antagonists, CGRP, Receptors, AM1, AM2, calcitonin-gene, related, peptide, CGRP8-37, (human)

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