Tocrifluor T1117

Cat. No. 2540

Tocrifluor T1117 C56H53Cl2N7O5 [1186195-59-4]

Price and Availability

For Tocrifluor T1117 pricing & availability please select your country from the drop down menu:
By clicking submit you agree to accept a cookie from Tocris Bioscience. For details, please read our privacy and cookie policy.

Chemical Name: N-(Piperidin-1-yl)-5-(4-(4-(3-(5-carboxamidotetramethylrhodaminyl)propyl))phenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide

Biological Activity

Fluorescent form of AM 251 (Cat. No. 1117). AM 251 conjugated with 5-carboxytetramethylrhodamine (5-TAMRA) that fluoresces at 543 nm excitation (590 nm emission). Displays GPR55 binding activity.

Technical Data

Soluble to 10 mM in DMSO
>95 %
Store at -20°C


Other Information

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Select another batch:
Safety Data Sheet: View Safety Data Sheet


Daly et al (2008) Visualisation of vascular cannabinoid receptors and their potential interaction with α1-adrenergic receptors. Vascular and Smooth Muscle Phys.Soc. Symposium.

Daly et al (2010) Fluorescent ligand binding reveals heterogeneous distribution of adrenoceptors and 'cannabinoid-like' receptors in small arteries. Br.J.Pharmacol. 159 787. PMID: 20136833.

Sylantyev et al (2013) Cannabinoid- and lysophosphatidylinositol-sensitive receptor GPR55 boosts neurotransmitter release at central synapses. Proc.Natl.Acad.Sci.U.S.A. 110 5193. PMID: 23472002.

Bruno et al (2014) Beyond radio-displacement techniques for identification of CB1 ligands: the first application of a fluorescence-quenching assay. Sci.Rep. 4 3757. PMID: 24441508.

If you know of a relevant citation for this product please let us know.

Keywords: Tocrifluor T1117, supplier, fluorescent, CB1, receptor, ligands, Fluorescent, Probes, cannabinoids, Receptors, cb1r, cb2r

Quick Order

Find multiple products by catalog number

divider line

Pain Research Product Guide

Pain Research Product Guide

Highlights over 280 products for Pain research. Request copy or view PDF today.

divider line

Neurodegeneration Research Product Guide

Neurodegeneration Product Guide

Updated in 2015, this guide highlights over 275 products for neurodegeneration research. Request copy or view PDF today.

divider line

Cannabinoid Review

Cannabinoid Receptor Ligands Scientific Review

Written by Roger Pertwee, an expert. Request copy or view PDF today.

divider line

Therapeutic Strategies in Schizophrenia

Written by J. Lieberman

Schizophrenia Life Science Poster

'Schizophrenia - Emerging Targets and Therapeutic Strategies' provides a summary of the targets and pathways representing the most promising strategies to pursue for novel drug development. Request copy today.

divider line

New Products in this Area

AM 6545

High affinity and selective CB1 antagonist

ML 193

Potent, selective GPR55 antagonist

Sign-up for new product e-alerts
divider line

Bio-Techne Events

ASCB 2015

ASCB 2015

December 12 - 16, 2015

San Diego, CA