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Tocrifluor T1117Cat. No. 2540 |
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Chemical Name: N-(Piperidin-1-yl)-5-(4-(4-(3-(5-carboxamidotetramethylrhodaminyl)propyl))phenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide |
Biological Activity
Novel fluorescent form of AM 251 (Cat. No. 1117). AM 251 conjugated with 5-carboxytetramethylrhodamine (5-TAMRA) that fluoresces at 543nm excitation (590nm emission). Displays GPR55 binding activity.Technical Data
M.Wt:The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Certificate of Analysis / Safety Data Sheet
References
Daly et al (2008) Visualisation of vascular cannabinoid receptors and their potential interaction with α1-adrenergic receptors. Vascular and Smooth Muscle Phys.Soc. Symposium.
Daly et al (2010) Fluorescent ligand binding reveals heterogeneous distribution of adrenoceptors and 'cannabinoid-like' receptors in small arteries. Br.J.Pharmacol. 159 787. PMID: 20136833.
Sylantyev et al (2013) Cannabinoid- and lysophosphatidylinositol-sensitive receptor GPR55 boosts neurotransmitter release at central synapses. Proc.Natl.Acad.Sci.U.S.A. 110 5193. PMID: 23472002.
If you know of a relevant citation for this product please let us know.
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Keywords: Tocrifluor T1117, supplier, fluorescent, CB1, receptor, ligands, Fluorescent, Probes, cannabinoids, Receptors, cb1r, cb2r
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