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MDL 73005EF hydrochlorideCat. No. 0411 |
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Chemical Name: 8-[2-(1,4-Benzodioxan-2-ylmethylamino)ethyl]-8-azaspiro[4.5]decane-7,9-dione hydrochloride |
Biological Activity
Potent and selective 5-HT1A receptor antagonist. Has partial agonist properties.Certificate of Analysis / Safety Data Sheet
References
Gartside et al (1990) Effects of MDL 73005EF on central pre-and-postsynaptic 5HT1A receptor function in the rat in vivo. Eur.J.Pharmacol. 191 391. PMID: 1964908.
Van der Hooff and Galvan (1991) Electrophysiology of the 5-HT1A ligand MDL 73005EF in the rat hippocampal slice. Eur.J.Pharmacol. 196 291. PMID: 1893914.
Buisson Defferier and Van den Buuse (1992) Cardiovascular effects of the 5-HT1A receptor ligand, MDL 73005EF, in conscious hypertensive rats. Eur.J.Pharmacol. 223 133. PMID: 1362161.
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Keywords: MDL 73005EF hydrochloride, supplier, Potent, selective, 5-HT1A, partial, agonists, Serotonin, Receptors, 5-HT1, MDL73005EF, hydrochloride
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