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CGRP (rat)

Cat. No. 1161

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Alternative Name: Calcitonin Gene-Related Peptide (rat)

Biological Activity

Endogenous neuropeptide; potent vasodilator which also exerts cardiovascular, pro-inflammatory and metabolic effects.

Technical Data

M.Wt:

3807

Formula:

C₁₆₂H₂₆₂N₅₀O₅₂S₂

Sequence:

SCNTATCVTHRLAGLLSRSGGVVKDNFVPTNVGSEAF

(Modifications: Disulfide bridge between 2 - 7, Phe-37 = C-terminal amide)

Solubility:

Soluble to 0.80 mg/ml in water

Storage:

Desiccate at -20°C

CAS No:

83651-90-5

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.

Resources

Certificate of Analysis / Safety Data Sheet

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Safety Data Sheet: View Safety Data Sheet

References

Morris et al (1984) Isolation and characterization of human calcitonin gene-related peptide. Nature 308 746. PMID: 6609312.

Brain et al (1985) Calcitonin gene-related peptide is a potent vasodilator. Nature 313 54. PMID: 3917554.

Poyner (1995) Pharmacology of receptors for calcitonin gene-related peptide and amylin. TiPS 16 424. PMID: 8578616.

Nakamura et al (1998) Calcitonin gene-related peptide as a GH secretagogue in human and rat pituitary somatotrophs. Brain Res. 807 203. PMID: 9757038.

Salim et al (1998) Calcitonin gene-related peptide potentiates nicotinic acetylcholine receptor-operated slow Ca²⁺ mobilization at mouse muscle endplates. Br.J.Pharmacol. 125 277. PMID: 9786499.

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