Cat. No. 0538
Chemical Name: trans-4-Hydroxy-2-butenoic acid
Biological ActivityBinds to the γ-hydroxybutyric acid (GHB) receptor with higher affinity than GHB itself. May be an endogenous ligand.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Certificate of Analysis / Safety Data Sheet
Vayer et al (1985) Natural occurrence of trans-gamma hydroxycrotonic acid in rat brain. Biochem.Pharmacol. 34 2401. PMID: 4015683.
Bourguignon et al (1988) Analogues of γ-hydroxybutyric acid. Synthesis and binding studies. J.Med.Chem. 31 893. PMID: 3361576.
Hechler et al (1993) Gamma hydroxybutyrate ligands posses antidopaminergic and neuroleptic-like activities. J.Pharmacol.Exp.Ther. 264 1406. PMID: 8095552.
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Keywords: trans-4-Hydroxycrotonic acid, supplier, GHB, receptor, ligand, GABAB, Receptors, GABAA, GABAC
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