Cat. No. 0896
Alternative Name: 5-MCA-NAT
Chemical Name: 5-Methoxycarbonylamino-N-acetyltryp
Biological ActivityBinds with high affinity to MT3 melatonin sites in hamster brain, and low affinity (and no efficacy) at MT1 and MT2 melatonin receptors and thus can be used to discriminate between the melatonin receptor subtypes.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Safety Data Sheet
Dubocovich (1995) Melatonin receptors: are there multiple subtypes? TiPS 16 50. PMID: 7762083.
Lucchelli et al (1997) Investigation into the contractile response of melatonin in the guinea-pig isolated proximal colon: the role of 5-HT4 and melatonin receptors. Br.J.Pharmacol. 121 1775. PMID: 9283717.
If you know of a relevant citation for this product please let us know.
View Related Products by Target
Keywords: GR 135531, supplier, High, affinity, melatonin, MT3, ligands, Receptors, GR135531, 5MCANAT
Find multiple products by catalog number
New Products in this Area
High affinity and selective EP2 receptor antagonistSAG
Potent Smoothened receptor agonist; activates the Hedgehog signaling pathwayDC 260126
FFA1 (GPR40) antagonistAR-C 118925XX
Selective, competitive P2Y2 receptor antagonistEPPTB
Trace amine 1 (TA1) receptor antagonist/inverse agonistEPPTB
Trace amine 1 (TA1) receptor antagonist/inverse agonistNIBR 189
Potent and selective EBI2 (GPR183) receptor antagonistONO AE3 208
High affinity and selective EP4 antagonistTCS 3035
April 12 - 15, 2015