Cat. No. 0896
Alternative Name: 5-MCA-NAT
Chemical Name: 5-Methoxycarbonylamino-N-acetyltryptamine
Biological ActivityBinds with high affinity to MT3 melatonin sites in hamster brain, and low affinity (and no efficacy) at MT1 and MT2 melatonin receptors and thus can be used to discriminate between the melatonin receptor subtypes.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Certificate of Analysis / Safety Data Sheet
Dubocovich (1995) Melatonin receptors: are there multiple subtypes? TiPS 16 50. PMID: 7762083.
Lucchelli et al (1997) Investigation into the contractile response of melatonin in the guinea-pig isolated proximal colon: the role of 5-HT4 and melatonin receptors. Br.J.Pharmacol. 121 1775. PMID: 9283717.
If you know of a relevant citation for this product please let us know.
View Related Products by Target
Keywords: GR 135531, supplier, High, affinity, melatonin, MT3, ligands, Receptors, GR135531, 5MCANAT
Find multiple products by catalog number
New Products in this Area
Potent and selective S1P4 agonistH2L5186303
Potent and selective LPA2 receptor antagonistMEDICA 16
FFA1 (GPR40) agonist. Also inhibits ATP citrate lyaseBX 471
Potent, selective CCR1 antagonistPF 04418948
Potent and selective EP2 receptor antagonistLatanoprost
FP prostaglandin receptor agonist; also exhibits agonist activity at EP1 and EP3 receptorsGRI 977143
Selective LPA2 receptor non-lipid agonistCYM 50260
Potent and selective S1P4 agonistG-36
Selective GPR30 antagonistStrontium chloride
Calcium sensing receptor (CaSR) agonistCS 2100
Selective S1P1 agonistSMANT hydrochloride
Inhibits Smoothened (Smo) accumulationTUG 891
Potent and selective GPR120 agonistIT1t dihydrochloride
Potent CXCR4 antagonistRuBi GABA trimethylphosphine
Caged GABA; inhibits neural activity
Win a Kindle
May 21 - 24, 2013
Booth Number: 32