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GR 135531

Cat. No. 0896

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Alternative Name: 5-MCA-NAT

Chemical Name: 5-Methoxycarbonylamino-N-acetyltryptamine

Biological Activity

Binds with high affinity to MT₃ melatonin sites in hamster brain, and low affinity (and no efficacy) at MT₁ and MT₂ melatonin receptors and thus can be used to discriminate between the melatonin receptor subtypes.

Technical Data

M.Wt:

275.31

Formula:

C₁₄H₁₇N₃O₃

Solubility:

Soluble to 100 mM in ethanol

Purity:

>97 %

Storage:

Store at RT

CAS No:

190277-13-5

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.

Resources

Certificate of Analysis / Safety Data Sheet

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Safety Data Sheet: View Safety Data Sheet

References

Dubocovich (1995) Melatonin receptors: are there multiple subtypes? TiPS 16 50. PMID: 7762083.

Lucchelli et al (1997) Investigation into the contractile response of melatonin in the guinea-pig isolated proximal colon: the role of 5-HT₄ and melatonin receptors. Br.J.Pharmacol. 121 1775. PMID: 9283717.

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Keywords: GR 135531, supplier, High, affinity, melatonin, MT3, ligands, Receptors, GR135531, 5MCANAT

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