QX 314 chloride
Cat. No. 2313
Chemical Name: N-(2,6-Dimethylphenylcarbamoylmethyl)triethylammonium chloride
Biological ActivityMembrane impermeable quaternary derivative of lidocaine, a blocker of voltage-activated Na+ channels.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Certificate of Analysis / Safety Data Sheet
Stichartz et al (1973) The inhibition of sodium currents in myelinated nerve by quaternary derivatives of lidocaine. J.Gen.Physiol. 62 37. PMID: 4541340.
Alreja and Aghajanian (1994) QX-314 blocks the potassium but not the sodium dependent components of the opiate response in locus coeruleus neurons. Brain Res. 639 320. PMID: 8205485.
Perkins and Wong (1995) Intracellular QX-314 blocks the hyperpolarization activated inward current Iq in hippocampal CA1 pyramidal cells. J.Neurophysiol. 72 911.
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Keywords: QX 314 chloride, supplier, Na+, channel, blockers, Sodium, NaV, Channels, voltage-gated, voltage-dependent, QX314, chloride
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