BVD 10

Cat. No. 2177

BVD 10 Ile-Asn-Pro-Ile-Tyr-Arg-Leu-Arg-Tyr-OMe

Price and Availability

For BVD 10 pricing & availability please select your country from the drop down menu:
By clicking submit you agree to accept a cookie from Tocris Bioscience. For details, please read our privacy and cookie policy.

Biological Activity

Highly selective NPY Y1 receptor antagonist. Ki values are 25.7, 1420, 2403 and 7100 nM at Y1, Y2, Y4 and Y5 receptors respectively. Devoid of agonist activity at Y4 receptors.

Licensing Information

Sold under license

Technical Data


(Modifications: Tyr-9 = Tyr-OMe)

Soluble to 1 mg/ml in 20% acetonitrile / water
Desiccate at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Select another batch:
Safety Data Sheet: View Safety Data Sheet


Balasubramaniam et al (2001) Highly selective and potent neuropeptide Y (NPY) Y1 receptor antagonists based on [Pro30, Tyr32, Leu34]NPY(28-36)-NH2 (BW1911U90). J.Med.Chem. 44 1479. PMID: 11334558.

Jois and Balasubramaniam (2003) Conformation of neuropeptide Y receptor antagonists: structural implications in receptor selectivity. Peptides 24 1035. PMID: 14499282.

Jois et al (2006) Modeling of neuropeptide receptors Y1, Y4, Y5, and docking studies with neuropeptide antagonist. J.Biomol.Struct.Dyn. 23 497. PMID: 16494499.

If you know of a relevant citation for this product please let us know.

View Related Products by Target

View Related Products by Product Action

Keywords: BVD 10, supplier, selective, Y1, antagonists, devoid, Y4, agonists, activity, Neuropeptide, Y, Receptors, NPY, BVD10, neuropeptides, NPY Receptor Antagonists

Quick Order

Find multiple products by catalog number

divider line

Peptide Hormone Receptors Product Listing

Peptide Hormone Receptors Product Listing

Highlights over 200 products for peptide hormone receptors. Request copy or view PDF today.

divider line

Appetite Modulation

Peptides Involved in Appetite Modulation Scientific Review

Written by Sonia A. Tucci, Lynsay Kobelis & Tim Kirkham. View PDF today.

divider line

Regulation of Vascular Reactivity by GPCRs

Written by J.J. Maguire and A.P. Davenport

Cardiovascular Life Science Poster

'Regulation of Vascular Reactivity by G-protein-coupled Receptors' summarizes the key GPCRs regulating vascular reactivity. Request copy today.

divider line

Gut Hormones and the Regulation of Appetite

Written by V.J. Taylor et al

Gut Hormones Life Science Poster

'Gut Hormones and the Regulation of Appetite' summaries the neuropeptide modulators and gut hormones that influence appetite. Request copy today.

divider line

New Products in this Area

RFRP-1 (human)

Potent NPFF receptor agonist

NTRC 824

Potent and selective non-peptide NTS2 antagonist

BA 1

Potent BRS-3 agonist; also NMBR and GRPR agonist

Sign-up for new product e-alerts
divider line

Twitter Updates

Follow @Tocris on Twitter

Follow us on Twitter!

Tocris is now actively tweeting. For regular updates on news, events and special offers, follow @Tocris on Twitter.