R&D Systems Inc. Tocris Bioscience Boston Biochem

Sarafotoxin S6b

Cat. No. 1174

Sarafotoxin S6b Cys-Ser-Cys-Lys-Asp-Met-Thr-Asp-Lys-Glu-Cys-Leu-Tyr-Phe-Cys-His-Gln-Asp-Val-Ile-Trp (Disulfide bridges: 1 - 15, 3 - 11)

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Biological Activity

Vasoconstrictor peptide; non-selective endothelin receptor agonist.

Technical Data

M.Wt:
2564
Formula:
C110H159N27O34S5
Sequence:
CSCKDMTDKECLYFCHQDVIW

(Modifications: Disulfide bridge between: 1-15, 3-11)

Solubility:
Soluble to 1 mg/ml in 20% acetonitrile
Storage:
Desiccate at -20°C
CAS No:
116303-65-2

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.

Certificate of Analysis / Safety Data Sheet

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Safety Data Sheet: View Safety Data Sheet

References

Aimoto et al (1990) Studies on the disulfide bridges of sarafotoxins. Chemical synthesis of sarafotoxin S6B and its homologue with different disulfide bridges. Biochem.Int. 21 1051. PMID: 2080919.

Bax et al (1994) Different endothelin receptors involved in endothelin-1- and sarafotoxin S6B-induced contractions of the human isolated coronary artery. Br.J.Pharmacol. 113 1471. PMID: 7889304.

Devadason and Henry (1997) Comparison of the contractile effects and binding kinetics of endothelin-1 and sarafotoxin S6b in rat isolated renal artery. Br.J.Pharmacol. 121 253. PMID: 9154335.

If you know of a relevant citation for this product please let us know.

View Related Products by Target

Keywords: Sarafotoxin S6b, supplier, Endothelin, receptor, agonists, non-selective, Non-Selective, ET, Receptors, ETA, ETB, SarafotoxinS6b

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