DAU 5884 hydrochloride
Cat. No. 2096
Chemical Name: 8-Methyl-8-azabicyclo-3-endo[3.2.1]oct-3-yl-1,4-dihydro-2-oxo-3(2H)-quinazolinecarboxylic acid ester hydrochloride
Biological ActivitySelective muscarinic M3 receptor antagonist. In bovine tracheal smooth muscle, inhibits methacholine-dependent effects on cell proliferation and muscle contractility.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Certificate of Analysis / Safety Data Sheet
Doods et al (1993) Characterization of muscarinic receptors in guinea-pig uterus. Eur.J.Pharmacol. 250 223. PMID: 8112383.
Roffel et al (1993) Cholinergic contraction of the guinea pig lung strip is mediated by muscarinic M2-like receptors. Eur.J.Pharmacol. 250 267. PMID: 8112384.
Gosens et al (2003) Muscarinic M3-receptors mediate cholinergic synergism of mitogenesis in airway smooth muscle. Am.J.Respir.Cell Mol.Biol. 28 257. PMID: 12540494.
Gosens et al (2004) Muscarinic M3 receptor-dependent regulation of airway smooth muscle contractile phenotype. Br.J.Pharmacol. 141 943. PMID: 14993104.
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Keywords: DAU 5884 hydrochloride, supplier, M3, receptor, antagonists, Muscarinic, Receptors, Acetylcholine, ACh, DAU5884, hydrochloride
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