Cat. No. 2085

Galnon Fmoc-β-cyclohexyl-Ala-Lys-(4-methyl-2-oxo-2H-1-benzopyran)

Price and Availability

For Galnon pricing & availability please select your country from the drop down menu:
By clicking submit you agree to accept a cookie from Tocris Bioscience. For details, please read our privacy and cookie policy.

Chemical Name: 3-Cyclohexyl-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-lysinamide

Biological Activity

Novel non-peptide galanin GAL1 and GAL2 receptor agonist (Ki values are 11.7 and 34.1 μM respectively). Stimulates insulin release in isolated pancreatic islets from normal and diabetic rats. Systemically active in vivo; displays anticonvulsant activity following i.p. administration in mice. Central and peripheral administration also transiently inhibits food intake in rats and mice.

Technical Data


(Modifications: Ala-1 = Fmoc-β-cyclohexyl-Ala, Lys-2 = Lys-(4-methyl-2-oxo-2H-1-benzopyran)

Soluble to 67.88 mg/ml in DMSO and to 16.97 mg/ml in ethanol with gentle warming
Desiccate at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Safety Data Sheet: View Safety Data Sheet


Saar et al (2002) Anticonvulsant activity of a nonpeptide galanin receptor agonist Proc.Natl.Acad.Sci.USA 99 7136. PMID: 12011470.

Abramov et al (2004) Regulation of feeding by galnon. Neuropeptides 38 55. PMID: 15003717.

Lu et al (2005) A role for galanin in antidepressant actions with a focus on the dorsal raphe nucleus. Proc.Natl.Acad.Sci. 102 874. PMID: 15647369.

Quynh et al (2005) Effects of galnon, a non-peptide galanin-receptor agonist, on insulin release from rat pancreatic islets. Biochem.Biophys.Res.Comm. 328 213. PMID: 15670772.

If you know of a relevant citation for this product please let us know.

View Related Products by Target

View Related Products by Product Action

Keywords: Galnon, supplier, Selective, non-peptide, GAL1, GalR1, agonists, Receptors, Galanin, Galanin Receptor Agonists

Quick Order

Find multiple products by catalog number

divider line

Peptide Hormone Receptors Product Listing

Peptide Hormone Receptors Product Listing

Highlights over 200 products for peptide hormone receptors. Request copy or view PDF today.

divider line

Appetite Modulation

Peptides Involved in Appetite Modulation Scientific Review

Written by Sonia A. Tucci, Lynsay Kobelis & Tim Kirkham. View PDF today.

divider line

Gut Hormones and the Regulation of Appetite

Written by V.J. Taylor et al

Gut Hormones Life Science Poster

'Gut Hormones and the Regulation of Appetite' summaries the neuropeptide modulators and gut hormones that influence appetite. Request copy today.

divider line

New Products in this Area

RFRP-1 (human)

Potent NPFF receptor agonist

NTRC 824

Potent and selective non-peptide NTS2 antagonist

BA 1

Potent BRS-3 agonist; also NMBR and GRPR agonist

Sign-up for new product e-alerts
divider line

Bio-Techne Events

ASCB 2015

ASCB 2015

December 12 - 16, 2015

San Diego, CA